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What is 4-AcO-DET?
Buy 4-AcO-DET (4-Acetoxy-N,N-diethyltryptamine) is a synthetic compound of the tryptamine class. It is the acetate ester of 4-HO-DET (Ethocin) and a higher homologue of 4-AcO-DMT. At Chemssupply.eu, we provide high-purity 4-AcO-DET as a stable fumarate or hydrochloride salt. As a premier EU-based chemical supplier, we ensure our 4-AcO-DET meets the analytical specifications required for advanced neurochemical and forensic research.
How It Works | | 98%+ Pure Research Chemicals | Chems Supply
In professional laboratory settings, 4-AcO-DET is researched as a suspected prodrug for 4-HO-DET. Upon contact with serum esterases, the acetoxy group is hypothesized to undergo hydrolysis, releasing the active phenolic tryptamine. According to research data available on NCBI PubMed, this compound is studied for its high affinity at the 5−HT 2A receptor subtype. Researchers utilize 4-AcO-DET to map the pharmacological differences between N,N-dimethyl and N,N-diethyl tryptamines, making it a critical reagent for Structure-Activity Relationship (SAR) mapping and LC-MS/MS calibration.
Benefits and Features
Superior Metabolic Stability: The 4-acetoxy substitution offers enhanced stability compared to the more oxygen-sensitive 4-hydroxy tryptamines, extending shelf-life for long-term study.
HPLC Verified Purity: We guarantee 98%+ verified purity, ensuring that your analytical results are not confounded by synthesis precursors like DET or 4-HO-DET.
Standardized Analytical Baseline: Exhibits a distinct molecular signature for mass spectrometry, assisting organizations like the European Chemicals Agency (ECHA) in chemical identification.
Stable Fumarate/HCl Salt: Provided in a robust salt form with excellent solubility in standard laboratory buffers and solvents.
REACH & ECHA Compliant: Fully documented according to the latest European chemical safety and distribution regulations (2026).
Safety and Handling
When you order 4-AcO-DET online in Europe, maintaining strict laboratory safety protocols is mandatory.
In-Vitro Laboratory Use Only: 4-AcO-DET is intended strictly for forensic, analytical, and academic research. It is not for human or animal consumption.
PPE Protocols: Researchers must wear nitrile gloves, laboratory coats, and eye protection. All chemical manipulation should occur in a certified fume hood.
Documentation: A comprehensive Material Safety Data Sheet (MSDS) is provided with every purchase to ensure compliant safety management in your facility.
Usage Guidelines and Storage
Optimal Storage: Store in a cool, dry, and dark environment (<25°C). To maintain peak chemical integrity for over 24 months, keep the container airtight and protected from moisture. Storage at -20°C is recommended for long-term preservation of the ester bond.
Analytical Application: Ideal for receptor binding assays, forensic toxicology screening, and investigating the enzymatic hydrolysis rates of acetoxylated tryptamines.
Disposal: Dispose of all chemical waste in accordance with your local hazardous-waste protocols.
Why Buy from Chemssupply.eu?
Chemssupply.eu is the leading authority for institutions looking to buy 4-AcO-DET online in Europe.
Direct EU Shipping: Dispatched from our internal EU facilities to ensure no customs interference and rapid delivery to Germany, France, Italy, and Spain.
Verified Batch Transparency: Access batch-specific purity certificates and verified lab data for every order to ensure research reliability.
Secure Payment Infrastructure: We support SEPA Bank Transfers and privacy-centric Cryptocurrencies (BTC, ETH, XMR).
Discreet Logistics: All orders are vacuum-sealed and shipped in neutral, professional packaging to preserve the chemical integrity of your research samples.
4-AcO-DET