High-Purity Synthetic Cannabinoid Analytical Standard

What is 4F-AMB?

Order 4F-AMB (4-Fluoro-AMB-PINACA) is a synthetic molecule of the indazole-3-carboxamide class. It is a potent agonist of the cannabinoid receptors and a structural analogue of the 5-fluorinated variant. At Chemssupply.eu, we provide professional-grade 4F-AMB in a stable crystalline form. As a premier EU-based chemical supplier, we ensure our 4F-AMB meets the analytical standards required for advanced forensic, toxicological, and neuropharmacological research.

Pharmacology and Mechanism

In laboratory and forensic settings, 4F-AMB is utilized to investigate the structure-activity relationship (SAR) of halogenated indazole cannabinoids.

Receptor Efficacy: Research data hosted on NCBI PubMed identifies 4F-AMB as a highly potent CB1 and CB2 receptor agonist. Researchers study its low nanomolar EC
50 values to understand the impact of terminal fluorine placement on receptor binding.

Analytical Mapping: 4F-AMB serves as a vital reference for identifying specific ester hydrolysis metabolites. These biomarkers are essential for differentiating between various synthetic cannabinoids in forensic casework conducted by organizations such as NPS Discovery.

Forensic Significance: Its distinct mass spectrometry signature is crucial for high-resolution screening and providing data to the European Union Early Warning System (EWS).

Chemical Properties

Formal Name: methyl (1-(4-fluoropentyl)-1H-indazole-3-carbonyl)-L-valin

Molecular Formula: C19 H26 FN3 O3

Molecular Weight: 363.43 g/mol

Form: Stable Fumarate Salt (Stable crystalline powder)

Purity: 98%+ HPLC Verified

REACH & ECHA Compliant: Fully documented according to current European Chemicals Agency (ECHA) safety standards (2026).

Safety and Handling

When you order 4F-AMB online in Europe, maintaining strict laboratory safety protocols is mandatory.

In-Vitro Laboratory Use Only: 4F-AMB is intended strictly for forensic, analytical, and academic research. It is not for human or animal consumption.

PPE Protocols: Researchers must wear nitrile gloves, laboratory coats, and eye protection. All chemical manipulation should occur in a certified, well-ventilated fume hood.

High Potency Caution: Given the potency of indazole cannabinoids, precision analytical scales and micro-measurement protocols are essential to prevent exposure and ensure data accuracy.

Documentation: A comprehensive Material Safety Data Sheet (MSDS) is provided with every purchase to ensure compliant safety management in your facility.

Usage and Storage Guidelines

Optimal Storage: Store in a cool, dry, and dark environment (<25°C). To maintain peak chemical integrity for over 12 months, keep the container airtight. Storage at -20°C is recommended for long-term preservation of the crystalline salt form.

Disposal: Dispose of all chemical waste in accordance with your local hazardous-waste protocols.